A Biomarker Study of Tivozanib in Subjects With Advanced Renal Cell Carcinoma

PHASE2CompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

January 31, 2011

Primary Completion Date

October 31, 2012

Study Completion Date

October 31, 2012

Conditions
Renal Cell Carcinoma
Interventions
DRUG

Tivozanib

Subjects will receive 1.5 mg tivozanib once daily beginning on Day 1 for 3 weeks followed by 1 week off treatment. One cycle will be defined as 4 weeks of treatment. Cycles will be repeated every 4 weeks.

Trial Locations (25)

78404

Coastal Bend Cancer Center, Corpus Christi

Unknown

Texas Oncology-Baylor, Charles A. Sammons Cancer Center, Dallas

BC Cancer Agency Vancouver Centre, Vancouver

Juravinski Cancer Center, Hamilton

Princess Margaret Hospital, Toronto

Sunnybrook Odette Cancer Center, Toronto, Toronto

Montreal General Hospital, Montreal

Southern Cancer Center, Mobile

Providence Health and Services, Burbank

David Geffen School of Medicine at UCLA, Los Angeles

Rocky Mountain Cancer Center, Denver

St. Francis Cancer Research Foundation, Beech Grove

Cancer Center of Kansas, Wichita

Medical Oncology, LLC, Baton Rouge

Dana Farber Cancer Institute, Boston

Cancer & Hematology Centers of Western Michigan, Grand Rapids

North Mississippi Hematology & Oncology Associates, Ltd., Tupelo

Comprehensive Cancer Centers of Nevada & US Oncology Research, Las Vegas

Mary Hitchcock Memorial Hospital, NH, Lebanon

University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill

Ohio State University, Columbus

Fox Chase Cancer Center, Philadelphia

The Jones Clinic, Germantown

The West Clinic, Memphis

Texas Oncology-Austin North, Austin

Sponsors
All Listed Sponsors
lead

AVEO Pharmaceuticals, Inc.

INDUSTRY