Tesetaxel in Chemotherapy-naive Patients With Progressive, Castration-resistant Prostate Cancer

PHASE2UnknownINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

February 28, 2011

Primary Completion Date

August 31, 2012

Study Completion Date

February 28, 2015

Conditions
Prostate Cancer
Interventions
DRUG

Tesetaxel

Tesetaxel capsules will be administered orally once every 21 days until progression, as defined by Prostate Cancer Working Group 2 (PCWG2) criteria. The duration of protocol therapy will not exceed 12 months. Treatment will be initiated at a dose of 27 mg/m2; dose escalation to a maximum of 35 mg/m2 is allowed in Cycle 2 depending on tolerability.

Trial Locations (4)

10065

RECRUITING

Memorial Sloan-Kettering Cancer Center, New York

53705

RECRUITING

University of Wisconsin Carbone Cancer Center, Madison

48109-5946

RECRUITING

University of Michigan Health System, Ann Arbor

08901

RECRUITING

The Cancer Institute of New Jersey, New Brunswick

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genta Incorporated

INDUSTRY