Effect of Probucol and/or Cilostazol on Mean IMT in Patients With Coronary Heart dIsease

PHASE4CompletedINTERVENTIONAL
Enrollment

342

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

December 31, 2016

Study Completion Date

March 31, 2017

Conditions
Hyperlipidemias
Interventions
DRUG

HMG-CoA Reductase Inhibitor

"During the study period, HMGCoA reductase inhibitor is continuously administered to the patients.~Dosage regimen: following the package insert of each HMGCoA reductase inhibitor"

DRUG

Probucol

"In addition to the continued HMGCoA reductase inhibitor treatment, probucol is administered.~Dosage regimen: probucol 250-mg tablet, oral administration twice daily with meal(breakfast and dinner)"

DRUG

Cilostazol

"In addition to the continued HMGCoA reductase inhibitor treatment, probucol and cilostazol are administered.~Dosage regimen: probucol 250-mg tablet, oral administration twice daily with meal(breakfast and dinner) Cilostazol 100-mg tablet, twice daily by the oral route"

Trial Locations (5)

602-715

Dong-A Medical Center, Seogu

135-710

Samsung Medical Center, Seoul

463-707

Seoul National University Bundang Hospital, Seongnam-si

110-744

Seoul National University Hospital, Seoul

156-707

Boramae Medical Center, Seoul

Sponsors
All Listed Sponsors
collaborator

Korea Otsuka Pharmaceutical Co., Ltd.

INDUSTRY

lead

Seoul National University Hospital

OTHER