A Single-centre, Randomised, Double-blind, Placebo-controlled, Four Way Crossover Phase I Study to Investigate the Effect on QT/QTc Interval of Ceftazidime NXL104 or Ceftaroline Fosamil NXL104, Compared With Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Volunteers

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 28, 2011

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions

Healthy Male Volunteers

Interventions

DRUG

NXL104

IV Solution

DRUG

Ceftaroline

IV Solution

DRUG

Placebo Infusion

IV Saline

DRUG

Ceftazidime

IV Solution

DRUG

Moxifloxacin

Tablet (1)

Trial Locations (1)

Research Site, Overland Park