Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts Esophagus

NACompletedINTERVENTIONAL
Enrollment

459

Participants

Timeline

Start Date

February 28, 2011

Primary Completion Date

October 31, 2013

Study Completion Date

October 31, 2013

Conditions
Barrett's Esophagus
Interventions
DEVICE

Sedated Endoscopy

The sedated esophagogastroduodenoscopy procedures were performed using a conventional high-definition endoscope (GIF-180, Olympus America, Center Valley, Pennsylvania) under conscious sedation with intravenous midazolam and fentanyl.

DEVICE

Transnasal Endoscopy

Unsedated transnasal endoscopy performed using the EndoSheath transnasal esophagoscope (TNL-5000, Vision Sciences). Topical anesthetic aerosol spray was applied to the posterior pharynx and nasal spray mixture was applied to the patients nares 10-15 minutes before the endoscopy procedure.

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

collaborator

American College of Gastroenterology

OTHER

lead

Mayo Clinic

OTHER