NCT01287390View on ClinicalTrials.gov

Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck

PHASE2CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

May 31, 2014

Study Completion Date

May 31, 2015

Conditions
Primary Non-operated Squamous Cell Carcinoma of Oral CavityPrimary Non-operated Squamous Cell Carcinoma of OropharynxPrimary Non-operated Squamous Cell Carcinoma of HypopharynxPrimary Non-operated Squamous Cell Carcinoma of Larynx
Interventions
PROCEDURE

video fluoroscopy

video fluoroscopy of swallowing function at baseline, 6 months and 12 months follow-up

PROCEDURE

extra imaging

For tumor response, 2 extra CT or Fludeoxyglucose (18F)-Positron Emission Tomography (PET)/Computed Tomography (CT), and/or Magnetic Resonance Imaging (MRI) will be performed.

OTHER

scoring acute toxicity

Acute toxicity scoring, based on Common Toxicity criteria (CTC) version 2.

OTHER

scoring of late toxicity

Scoring of late toxicity with the 'late effects in normal tissues subjective, objective, management and analytic'(LENT-SOMA) scale.

OTHER

scoring quality of life (QOL)

Quality of life is scored with the Quality of Life Questionnaire of the 'European Organisation for Research and Treatment of Cancer' (EORTC QOL-C30) and the Head and Neck Cancer Specific Quality of Life Questionnaire (QLQ-H\&N 35).

Trial Locations (2)

3000

University Hospital Leuven, Leuven

9000

University Hospital Ghent, Ghent

All Listed Sponsors
lead

University Hospital, Ghent

OTHER

NCT01287390 - Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck | Biotech Hunter | Biotech Hunter