Mycophenolate Mofetil in Patients With Progressive Idiopathic Membranous Nephropathy

PHASE3CompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

May 31, 2016

Study Completion Date

May 31, 2016

Conditions
Glomerulonephritis, Membranous
Interventions
DRUG

Mycophenolate mofetil, low dose steroid

"Mycophenolate Mofetil: Myconol capsule 250mg, Myconol 500 mg bid per day (less than 50kg), 750 \~ 1000 mg bid per day (more than 50kg)~Steroid: Methylprednisone 4mg tablet or Prednisolone 5mg tablet or Deflazacort 6mg tablet. Prednisolone dose: 0.15mg/kg up to a maximum dose of 15mg/day~Duration: 48 weeks"

DRUG

Cyclosporin, low dose steroid

"Cyclosporin: Implanta soft cap (cyclosporin microemulsion) 25mg/100mg, starting dose of 4mg/kg per day and titrate according to investigator's decision based on cyclosporin trough level (100±50 ng/ml)~Steroid: same dosage with active comparator goup~Duration: 48 weeks"

Trial Locations (9)

602-715

Dong-A University Medical Center, Busan

Unknown

Inje University Haeundae Paik Hospital, Busan

700-721

Kyungpook National University Hospital, Daegu

701-600

Daegu Fatima Hospital, Daegu

705-717

Yeungnam University Medical Center, Daegu

110-799

Seoul National University Hospital, Seoul

120-752

Yonsei University Hospital, Seoul

156-707

Boramae Medical Center, Seoul

682-714

Ulsan University Hospital, Ulsan

Sponsors
All Listed Sponsors
collaborator

Hanmi Pharmaceutical Company Limited

INDUSTRY

lead

Kyungpook National University Hospital

OTHER