Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

January 31, 2011

Primary Completion Date

July 31, 2016

Study Completion Date

October 31, 2016

Conditions
NeurofibromatosisNF1Neurofibromas
Interventions
DRUG

Tasigna

Following enrollment each subject will initially receive Tasigna orally at 200 mg twice daily for two weeks. If tolerated, the dose will be increased to 300 mg twice daily after a minimum of two weeks and will be increase to a maximum dose of 400mg twice daily after an additional two weeks if tolerated.

Trial Locations (1)

46202

Riley Hospital for Children, Indianapolis

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

Indiana University

OTHER