Start Date
July 31, 2011
Primary Completion Date
April 30, 2014
Study Completion Date
December 31, 2014
Placebo, Velcade and dexamethasone
Siltuximab 11 mg/kg as 1 hour IV infusion on Day 1 of every cycle
Siltuximab, Velcade and dexamethasone
Given in 21-day treatment cycles
Iowa City
Boston
Toledo
Willow Grove
Milwaukee
Adelaide
Camperdown
Heidelberg
Parkville
Prahran
Edegem
Liège
Turnhout
Yvoir
Plovdiv
Sofia
Varna
Toronto
Hradec Králové
Liberec
Prague
Gandhinagar Guiarat
Apeldoorn
Deventer
Zwolle
Christchurch
Grafton
Nz 9 Takapuna Auckland
Palmerston North
Brzozów
Gdansk
Lodz
Opole
Wroclaw
Hwasun Gun
Seoul
Ankara
Bursa
Edirne
Cherkassy
Dnipro
Kharkiv
Khmelnitskiy
Kiev
Odesa
Simferopol
Vinnitsa
Nottingham
Lead Sponsor
Centocor, Inc.
INDUSTRY