366
Participants
Start Date
August 13, 2012
Primary Completion Date
December 30, 2016
Study Completion Date
December 30, 2016
Nissen fundoplication
laparoscopic antireflux surgery
baclofen
"Baclofen will be prescribed in a dose of 5 mg three times a day (TID) with meals.~The dose of baclofen will be increased by 5 mg TID every week until a total dose of 20 mg TID has been achieved."
Desipramine
Dose of 25 mg at bedtime (HS) for 1 week, then 50 mg HS for 1 week, then 100 mg HS until the next quarterly visit.
Syracuse VA Medical Center, Syracuse, NY, Syracuse
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore
Durham VA Medical Center, Durham, NC, Durham
Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC, Salisbury
Birmingham VA Medical Center, Birmingham, AL, Birmingham
VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Kansas City VA Medical Center, Kansas City, MO, Kansas City
VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas
Michael E. DeBakey VA Medical Center, Houston, TX, Houston
Southern Arizona VA Health Care System, Tucson, AZ, Tucson
VA Long Beach Healthcare System, Long Beach, CA, Long Beach
VA Loma Linda Healthcare System, Loma Linda, CA, Loma Linda
VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle
VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
VA Office of Research and Development
FED