Maximal Androgen Depletion Followed by Randomization of Maximal Androgen Ablation With Molecular Targeted Therapies

1000 mg by mouth each day of a 28 day cycle.

5 mg by mouth twice daily of a 28 day cycle.

37.5 mg by mouth daily for two weeks followed by a week of rest in a 28 day cycle.

100 mg by mouth each day of a 28 day cycle.