Docetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

January 31, 2001

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions
Prostate Cancer
Interventions
DRUG

Docetaxel

Given by an IV infusion over 1 hour on day 2 of a three-week cycle

DRUG

Dexamethasone

Orally 12 hours and 1 hour before docetaxel and again 12 hours after docetaxel

DRUG

Estramustine

Taken orally three times a day for 5 days for the first part of every three week cycle

DRUG

Zoladex

Given subcutaneously for 4 doses every three months

DRUG

Casodex

Taken orally once a day for 6 months

PROCEDURE

Radical Prostatectomy

after the chemo and hormonal therapy all patients have a radiacal prostatectomy

Trial Locations (1)

02115

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Walter Reed Army Medical Center

FED

lead

Beth Israel Deaconess Medical Center

OTHER

NCT01250717 - Docetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate Cancer | Biotech Hunter | Biotech Hunter