A Study to Evaluate the Safety and Antitumor Activity in Subjects With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

162

Participants

Timeline

Start Date

October 31, 2010

Primary Completion Date

July 31, 2015

Study Completion Date

October 31, 2015

Conditions
Advanced Solid TumorsAdvanced Recurrent Ovarian Tumors
Interventions
DRUG

MEDI3617

Participants will receive MEDI3617 via IV infusion in each cycle until unacceptable toxicity, initiation of alternative anticancer treatment, documented disease progression, or other reasons.

DRUG

Bevacizumab

Participants will receive bevacizumab via IV infusion in each cycle until unacceptable toxicity, initiation of alternative anticancer treatment, documented disease progression, or other reasons.

DRUG

Paclitaxel

Participants will receive paclitaxel via IV infusion in each cycle until unacceptable toxicity, documented disease progression, or other reasons.

DRUG

Carboplatin

Participants will receive carboplatin via IV infusion in each cycle until unacceptable toxicity, documentation of disease progression, or other reasons.

Trial Locations (10)

Unknown

Research Site, Los Angeles

Research Site, Stanford

Research Site, Lafayette

Research Site, Baltimore

Research Site, Boston

Research Site, Detroit

Research Site, Buffalo

Research Site, New York

Research Site, Philadelphia

Research Site, Nashville

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MedImmune LLC

INDUSTRY