Safety and Efficacy Study of BMS-908662 in Combination With Ipilimumab in Subjects With Advanced Melanoma

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

January 31, 2011

Primary Completion Date

November 30, 2012

Study Completion Date

November 30, 2012

Conditions
Melanoma
Interventions
DRUG

BMS-908662

Capsules, Oral, escalating doses starting at 25 mg, Q 12 h daily, Continuously

DRUG

BMS-908662

Capsules, Oral, escalating doses starting at 25 mg Q 12 h daily for 3 weeks with 3 weeks interval for 4 cycles, then Q12 h daily for 3 weeks every 12 weeks, Continuously

DRUG

Ipilimumab

Vial, IV, escalating doses starting at 3 mg/kg, Once every 3 weeks for 6 weeks, then once every 12 weeks, Continuously

DRUG

Ipilimumab

Vial, IV, escalating doses starting at 3 mg/kg, Once every 6 weeks for 4 cycles, then once every 12 weeks, Continuously

Trial Locations (2)

10065

Jedd D. Wolchok, Md,Phd, New York

33612

H. Lee Moffitt Cancer Center & Research Institute, Tampa

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT01245556 - Safety and Efficacy Study of BMS-908662 in Combination With Ipilimumab in Subjects With Advanced Melanoma | Biotech Hunter | Biotech Hunter