Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects

Saline infusion for 56 minutes

PF-02545920 10 mg single dose

"Ketamine 0.23 mg/kg bolus over one min; and 0.58 mg/kg/hour maintenance for 56 minutes~PF-02545920 10 mg tablet"

PF-02545920 10 mg tablet single dose

Saline infusion for 56 minutes

Placebo tablet single dose

Ketamine 0.23 mg/kg bolus over one min; and 0.58 mg/kg/hour maintenance for 56 minutes

Placebo tablet single dose