Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana

PHASE3CompletedINTERVENTIONAL
Enrollment

417

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

December 31, 2012

Study Completion Date

February 28, 2013

Conditions
Pregnancy Complicated by Malaria as Antepartum Condition
Interventions
DRUG

artesunate-amodiaquine

The 452 pregnant women in this arm will receive artesunate-amodiaquine tablets(artesunate 4mg/kg and amodiaquine 10mg/kg in twelve hourly doses over 3 days

DRUG

Dihydroartemisinin-piperaquine

a fixed-dose combination to be administered to the other 452 pregnant women in this arm at an estimated total dosing of 6.75mg/kg dihydroartemisinin and 55mg/kg piperaquine over 3 days

Trial Locations (1)

Unknown

St.Michael's Hospital, Pramso, Kumasi

All Listed Sponsors
collaborator

Malaria Capacity Development Consortium

UNKNOWN

lead

Kwame Nkrumah University of Science and Technology

OTHER

NCT01231113 - Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana | Biotech Hunter | Biotech Hunter