606
Participants
Start Date
November 30, 2011
Primary Completion Date
November 30, 2014
Study Completion Date
August 31, 2016
curcumin
Patients will take the study medication (500 mg x 4 capsules, twice daily \[BID\]) for two days leading up to repair, totaling 4000 mg per day. They will take a dose (2000 mg) the morning of repair, at the same time as regular medications not held for surgery. While they are on call to the operating room, they will take another dose of 2000 mg and then another 2000 mg dose 6 hours after the repair. Final dose is administered the morning after repair.
placebo
The placebo will look, smell, taste, and in every way be identical to the active drug. Patients will take the study medication in the exact same manner as the curcumin regimen.
University of Calgary, Calgary
University of Alberta Hospital, Edmonton
St. Boniface Hospital, Winnipeg
Sudbury Regional Hospital, Greater Sudbury
Hamilton General Hospital, Hamilton
London Health Sciences Centre, London
The Ottawa Hospital, Civic Campus, Ottawa
Sunnybrook Health Sciences Centre, Toronto
St. Michael's Hospital, Toronto
Maisonneuve-Rosemont Hospital, Montreal
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
OTHER