Study of AA4500 in the Treatment of Peyronie's Disease

PHASE3CompletedINTERVENTIONAL
Enrollment

418

Participants

Timeline

Start Date

October 31, 2010

Primary Completion Date

March 31, 2012

Study Completion Date

March 31, 2012

Conditions
Peyronie's Disease
Interventions
BIOLOGICAL

AA4500

2 injections separated by at least 24 hours but not more than 72 hours. At least 24 hours but not more than 72 hours after the 2nd injection of the treatment cycle, the investigator will model the plaque (ie, gradual, gentle stretching of the flaccid penis in the direction opposite to the curvature). Treatment may be repeated after 42 days (± 5 days) for up to 4 treatment cycles.

BIOLOGICAL

Placebo

2 injections separated by at least 24 hours but not more than 72 hours. At least 24 hours but not more than 72 hours after the 2nd injection of the treatment cycle, the investigator will model the plaque (ie, gradual, gentle stretching of the flaccid penis in the direction opposite to the curvature). Treatment may be repeated after 42 days (± 5 days) for up to 4 treatment cycles.

Trial Locations (34)

10016

University Urology Associates, New York

10577

Michael A. Werner, MD, PC, Purchase

11021

Bruce R. Gilbert, MD, PhD, PC, Great Neck

12208

The Capital Region Medical Research Foundation @ the Urological Institute of Northeastern New York, Albany

21061

Chesapeake Urology Research Assoc., Glen Burnie

21204

Chesapeake Urology Research Assoc., PA, Towson

27599

Universitiy of North Carolina School of Medicine Div. of Urology, Chapel Hill

27710

Duke University Medical Center Division of Urologic Surgery, Durham

32803

Winter Park Urology Associates, Orlando

33180

South Florida Medical Research, Aventura

36608

Costal Clinical Research, Inc., Mobile

46825

Northeast Indiana Research, LLC, Fort Wayne

47130

Metropolitan Urology, P.S.C., Jeffersonville

48109

University of Michigan, Ann Arbor

66211

Kansas City Urology Care, P.A. Research Department, Overland Park

70112

Tulane University Health Sciences Center Dept. of Urology, New Orleans

71106

Regional Urology L.L.C., Shreveport

75010

Research Across America, Carrollton

75231

Urology Clinics of North Texas, PA, Dallas

78229

Urology San Antonio Research, PA, San Antonio

80211

The Urology Center of Colorado, Denver

83642

Idaho Urologic Institute, Meridian

85048

Connect Clinical Research Center (CCRC), Phoenix

92653

So. Orange County Medical Research Center, Laguna Hills

99508

Alaska Clinical Research Center, LLC, Anchorage

06762

Connecticut Clinical Resarch Center, LLC, Middlebury

08103

Cooper Health System, Camden

08648

AdvanceMed Research, Lawrenceville

02906

The Miriam Hospital, Providence

NSW 2217

Urology Sydney, Kogarah

NSW 2000

Health Pac Medical Centre, Sydney

QLD 4000

AusTrials Pty Limited, Brisbane

VIC 3193

Bayside Urology, Mentone

WA 6009

Keogh Institute for Medical Research, Nedlands

Sponsors
All Listed Sponsors
lead

Endo Pharmaceuticals

INDUSTRY