Study of AA4500 in the Treatment of Peyronie's Disease

PHASE3CompletedINTERVENTIONAL
Enrollment

418

Participants

Timeline

Start Date

September 30, 2010

Primary Completion Date

April 30, 2012

Study Completion Date

April 30, 2012

Conditions
Peyronie's Disease
Interventions
BIOLOGICAL

AA4500

2 injections separated by at least 24 hours but not more than 72 hours. At least 24 hours but not more than 72 hours after the 2nd injection of the treatment cycle, the investigator will model the plaque (ie, gradual, gentle stretching of the flaccid penis in the direction opposite to the curvature). Treatment may be repeated after 42 days (± 5 days) for up to 4 treatment cycles.

BIOLOGICAL

Placebo

2 injections separated by at least 24 hours but not more than 72 hours. At least 24 hours but not more than 72 hours after the 2nd injection of the treatment cycle, the investigator will model the plaque (ie, gradual, gentle stretching of the flaccid penis in the direction opposite to the curvature). Treatment may be repeated after 42 days (± 5 days) for up to 4 treatment cycles.

Trial Locations (34)

11235

Division of Urology at Maimonides Medical Center, Brooklyn

17604

Urological Associates of Lancaster, Lancaster

19010

Urology Health Specialists,LLC, Bryn Mawr

21204

Chesapeake Urology Research Associates, Baltimore

21287

Johns Hopkins Hospital, Baltimore

23502

Urology of Virginia - Sentara Medical Group, Norfolk

27403

Alliance Urology Specialists, PA, Greensboro

27607

Wake Urological Associates, Raleigh

31904

Southeastern Medical Research Institute, Columbus

33414

Palm Beach Urology Associates, Wellington

34747

DCT-Celebration, LLC dba Discovery Clinical Trials, Celebration

35209

Urology Centers of Alabama, PC, Homewood

37043

Alpha Clinical Research, LLC, Clarksville

45212

Tristate Urologic Services PSC Inc. dba TUG Research, Cincinnati

46123

Urology of Indiana LLC, Avon

53226

Medical College of Wisconsin, Department of Urology, Milwaukee

55905

Mayo Clinic at Rochester, Dept. of Urology, Rochester

60515

DuPage Medical Group, Downers Grove

76017

Urology Associates of North Texas, Arlington

77030

Baylor College of Medicine, Department of Urology, Houston

84107

Salt Lake Research, PLLC, Salt Lake City

85050

HOPE Research Institute, LLC, Phoenix

91505

Urology Associates Medical Group, Burbank

92120

San Diego Sexual Medicine, San Diego

92660

California Professional Research, Newport Beach

06052

Grove Hill Clinical Research, Grove Hill Medical Center, New Britain

06511

The Urology Center, PC, New Haven

02445

Mens Health Boston, Brookline

07601

Center for Reproductive Medicine, Hackensack

NSW 2065

Australian Centre for Sexual Health, St Leonards

NSW 2145

Western Urology, Westmead

QLD 4019

AusTrials, Kipparing

SA 5041

Repatriation General Hospital, Daws Park

VIC 3144

Australian Urology Associates Pty Ltd, Malvern

Sponsors
All Listed Sponsors
lead

Endo Pharmaceuticals

INDUSTRY