Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene

PHASE2CompletedINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

April 8, 2011

Primary Completion Date

March 1, 2013

Study Completion Date

September 1, 2014

Conditions
NSCLCNon Small Cell Lung Cancer
Interventions
DRUG

OSI-906

As of 01 March 2013, OSI-906 is no longer being administered

DRUG

Erlotinib

Erlotinib administered orally

DRUG

Placebo

As of 01 March 2013, the matching placebo is no longer being administered

Trial Locations (29)

852

Pamela Youde Nethersole Eastern Hospital, Chai Wan

10021

Memorial Sloan Kettering Cancer Center, New York

10400

National Cancer Institute, Phayathai

21231

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore

29425

Medical University of South Carolina, Charleston

31804

University of Tennessee Cancer Institute, Memphis

33331

Cleveland Clinic Florida, Weston

33612

H. Lee Moffitt Cancer Center and Research Institute, Tampa

37232

Vanderbilt University Medical Center, Nashville

40002

Khon Kaen University, Khon Kaen

48201

Karmanos Cancer Institute, Detroit

50002

Maharaj Nakorn Chiangmai, Chiang Mai

60611

Northwestern Memorial Hospital, Chicago

60612

Rush University Medical Center, Chicago

90110

Songklanagarind Hospital, Prince of Songkla University, Songkhla

92093

University of California, San Diego/Moores Cancer Center, La Jolla

98104

Swedish Cancer Institute, Seattle

98109

Seattle Cancer Care Alliance University of Washington, Seattle

135710

Samsung Medical Center, Seoul

136705

Korea University Anam Hospital, Seoul

138736

Asan Medical Center, Songpa-gu

258499

Oncocare Cancer Center, Singapore

308433

Johns Hopkins Singapore International Medical Centre, Singapore

519809

Chonnam National University Hwasun Hospital, Ilsimri

L8V 5C2

Juravinski Cancer Centre, Hamilton

N6A 4L6

London Regional Cancer Program, London

M5G 2M9

Princess Margaret Hospital, Toronto

H3T 1E2

Jewish General Hospital, Montreal

463-707

Seoul National University Bundang Hospital, Seongnam-si

Sponsors
All Listed Sponsors
lead

Astellas Pharma Inc

INDUSTRY

NCT01221077 - Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene | Biotech Hunter | Biotech Hunter