Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis

PHASE4CompletedINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

December 31, 2010

Study Completion Date

June 30, 2011

Conditions
Hip Osteoarthritis
Interventions
DRUG

zoledronic acid

The patients in the active-treatment group will receive a single 5 mg dose of zoledronic acid intravenously just prior to release from the hospital (about 5th day post-surgery) as an adjunct therapy. The control group will receive a placebo (saline) infusion. All infusions will be given 100 ml in volume and infused over a period of 15 minutes with a pre- and post-infusion flush with normal saline.

Trial Locations (1)

20520

Turku University Hospital, Turku

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Academy of Finland

OTHER

collaborator

Novartis

INDUSTRY

collaborator

Stryker Nordic

INDUSTRY

lead

Turku University Hospital

OTHER_GOV