1,012
Participants
Start Date
September 30, 2011
Primary Completion Date
February 28, 2017
Study Completion Date
February 28, 2017
Ranolazine
At enrollment, patients will be randomized to ranolazine or placebo. In the active drug arm each patient will be started on a 500 mg twice a day dose for one week with subsequent increase to 1000 mg twice a day at beginning of second week.
Weill Cornell Medical College/New York Presbyterian Hospital, New York
St. Luke's-Roosevelt Hospital, New York
SUNY Downstate Medical Center, Brooklyn
New York Methodist Hospital, Brooklyn
Maimonides Medical Center, Brooklyn
Stony Brook University Medical Center,, Stony Brook
Hudson Valley Heart Center, Poughkeepsie
University of Rochester, Rochester
University of Pittsburgh Medical Center-Presbyterian, Pittsburgh
VA Pittsburgh Healthcare Center, Pittsburgh
Lancaster Heart & Stroke Foundation, Lancaster
Doylestown Cardiology Associates - VIAA, Doylestown
Doylestown Health Cardiology/Central Bucks, Doylestown
Abington Medical Specialists, Abington
Lankenau Institute for Medical Research, Wynnewood
Drexel University College of Medicine, Philadelphia
Thomas Jefferson University, Philadelphia
Washington Electrophysiology/Cardiovascular Research Institute, Washington D.C.
MedStar Southern Maryland Hospital Center, Clinton
Walter Reed NMMC, Portsmouth
University of Maryland Medical Center, Baltimore
Johns Hopkins University, Baltimore
University of Virginia Health System, Charlottesville
Virginia Commonwealth University, Richmond
Cardiovascular Associates Ltd., Chesapeake
CAMC Institute, Charleston
Durham VA Medical Center, Durham
Duke University Medical Center, Durham
Georgia Health Sciences University, Augusta
Georgia Arrhythmia Consultants, Macon
University of Florida Health Science Center at Jacksonville, Jacksonville
Tallahassee Research Institute, Inc., Tallahassee
University of Florida/Cardiovascular Medicine, Gainesville
Florida Hospital, Orlando
Bay Area Cardiology Associates, P.A., Brandon
Watson Clincia Center for Research Inc., Lakeland
Vanderbilt University Medical Center, Nashville
The Stern Cardiovascular Center, Germantown
University of Mississippi Medical Center, Jackson
Central Baptist Hospital, Lexington
The Toledo Hospital/Northwest Ohio Cardiology Consultants, Toledo
The MetroHealth System - Heart and Vascular Dept., Cleveland
The Lindner Center for Research & Education, Cincinnati
University of Cincinnati, Cincinnati
LaPorte Hospital, Hobart
Peakview Research Center, Fort Wayne
William Beaumont Hospital - Royal Oak, Royal Oak
Michigan Heart, Ypsilanti
Henry Ford Hospital, Detroit
University of Iowa, Iowa City
Aurora St. Luke's Medical Center, Milwaukee
Wheaton Franciscan All Saints, Racine
Marshfield Clinic, Marshfield
University of Minnesota, Minneapolis
St. Luke's Hospital Association of Duluth, Duluth
University of Chicago Hospital, Chicago
Kansas City Heart Foundation, Kansas City
University of Missouri, Columbia
Louisiana State University Health Sciences Center- New Orleans, New Orleans
Arkansas Cardiology, Little Rock
Cardiopulmonary Research Science and Technology Inst., Dallas
Medicus Alliance CRO, Inc, Houston
Texas Cardiac Arrhythmia Research Foundation, Austin
University of Colorado Health - MHS, Colorado Springs
University of Arizona, Tucson
Good Samaritan Hospital, Los Angeles
Huntington Memorial Hospital, Pasadena
Sequoia Hospital, East Palo Alto
Delta Heart and Medical Clinic, Stockton
Regional Cardiology Associates, Sacramento
Oregon Health & Science University, Portland
Portland VA Medical Ctr, Portland
Cardiac Study Center, Tacoma
Kootenai Heart Clinics, LLC, Spokane
Bridgeport Hospital, Bridgeport
Hartford Hospital, Hartford
Tufts-New England Medical Center, Boston
Lahey Clinic, Burlington
University of Massachusetts-Worchester, Worcester
Cooper University Hospital, Camden
Morristown Memorial Hospital- Gagnon Cardiovascular Institute, Morristown
The Valley Hospital, Ridgewood
Brigham and Women's Cardiovascular Associates, Warwick
University of Calgary, Calgary
Royal Alexandra Hospital, Edmonton
Queen's University, Kingston
Montreal Heart Institute, Montreal
McGill University Health Centre, Montreal
CHUS (Sherbrooke University), Sherbrooke
IUCPQ, Québec
University of Rochester
OTHER