A Phase 1, Open Label, Placebo-Controlled Study to Evaluate the Effect of GSK1349572 on Iohexol and Para-Aminohippurate Clearance in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

October 31, 2010

Primary Completion Date

November 30, 2010

Study Completion Date

November 30, 2010

Conditions
Infections, Human Immunodeficiency Virus and Tuberculosis
Interventions
DRUG

GSK1349572

GSK1349572 is an experimental drug in the integrase inhibitor class of drugs to treat human immunodeficiency virus (HIV)

DRUG

Placebo

Placebo is a tablet with no drug in it.

DRUG

Iohexol Injection

Iohexol is an FDA approved radiologic contrast medium

DRUG

Para-aminohippurate infusion

Para-aminohippurate is an agent to measure effective renal plasma flow.

Trial Locations (1)

55404

GSK Investigational Site, Minneapolis

Sponsors

Lead Sponsor

Collaborators (2)

All Listed Sponsors
collaborator

Shionogi

INDUSTRY

collaborator

GlaxoSmithKline

INDUSTRY

lead

ViiV Healthcare

INDUSTRY