A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

September 30, 2010

Primary Completion Date

April 30, 2012

Conditions
Parkinson's Disease With Cognitive Impairments
Interventions
DRUG

safinamide

Safinamide will be provided in tablets equivalent to 50 mg in blisters. After randomization, patients receiving safinamide will take two 50 mg tablets once per day for 12 weeks (weeks 1-12). During the open label phase, patients will receive 100mg of safinamide once per day (two 50 mg tablets) for 12 weeks (weeks 13-24).

DRUG

placebo

Identical placebo tablets will be provided in blisters. After randomization, patients receiving placebo will take two tablets once per day for 12 weeks (weeks 1-12). During the open label phase, patients will receive 100mg of safinamide once per day (two 50 mg tablets) for 12 weeks (weeks 13-24).

Trial Locations (15)

Unknown

The Parkinson's Institute, Sunnyvale

Mayo Clinic Florida, Jacksonville

Emory University, Atlanta

Northwestern University, Chicago

Rush University Medical Center, Chicago

Johns Hopkins University, Baltimore

US Medical Information Located in, Rockland

Cleveland Clinic, Cleveland

Baylor College of Medicine Parkinson's Disease Center and Movement Disorders Clinic, Houston

Hospital Clinic de Barcelona, Barcelona

Hospital De La Santa Creui Sant Pau, Barcelona

Hospital General de Catalunya, Barcelona

USP Institut Universitari Dexeus, Barcelona

Hosptial General Univ Gregorio Maranon, Madrid

Hospital Mutual de Terrassa, Terrassa - Barcelona

Sponsors
All Listed Sponsors
lead

Newron Pharmaceuticals SPA

INDUSTRY

NCT01211587 - A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease | Biotech Hunter | Biotech Hunter