Study of Revlimid With Doxil and Avastin for Patients With Platinum Resistant Ovarian Cancer

PHASE1TerminatedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

September 30, 2010

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2012

Conditions
Ovarian CancerEpithelial Ovarian CancerFallopian Tube CarcinomaPrimary Peritoneal Carcinoma
Interventions
DRUG

Lenalidomide, Liposomal Doxorubicin, Bevacizumab

"At the expansion phase: Revlimid 20 mg (days 1-21), Doxil 30 mg/m2 on Day 1 and Avastin 15 mg/kg on Day 1, every 3 weeks. If this regimen is not cumulatively tolerable, Avastin will be administered every other course.~Patients will be received up to 6 cycles or disease progression, followed by Revlimid maintenance at 25 mg PO q Day for 3 weeks every 4 weeks in patients with stable disease."

DRUG

Revlimid, Doxil, Avastin

At the expansion phase: Revlimid 20 mg (days 1-21), Doxil 30 mg/m2 on Day 1 and Avastin 15 mg/kg on Day 1, every 3 weeks. If this regimen is not cumulatively tolerable, Avastin will be administered every other course. Patients will be received up to 6 cycles or disease progression, followed by Revlimid maintenance at 25 mg PO q Day for 3 weeks every 4 weeks in patients with stable disease.

Trial Locations (1)

87106

University of New Mexico Cancer Center, Albuquerque

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Celgene Corporation

INDUSTRY

lead

New Mexico Cancer Research Alliance

OTHER