Genasense, Carboplatin, Paclitaxel (GCP) Combination in Uveal Melanoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

December 31, 2010

Primary Completion Date

September 30, 2013

Study Completion Date

September 30, 2013

Conditions
Melanoma
Interventions
DRUG

Genasense

900 mg by vein over 1 hour on Days 1, 3, and 5 of a 21 day cycle.

DRUG

Paclitaxel

175 mg/m\^2 by vein over 3 hours on Day 3 of a 21 day cycle following Genasense.

DRUG

Carboplatin

"Carboplatin starting dose in mg (AUC= 6) is administered over 30 minutes IV Piggyback (IVPB). Carboplatin will be dosed after Paclitaxel dose on Day 3 every 3 weeks.~The total dose of Carboplatin is calculated using a formula based upon a participant's glomerular filtration rate (GFR in mL/min) and Carboplatin target area under the concentration (AUC)."

Trial Locations (1)

77030

UT MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genta Incorporated

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER