Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome

PHASE3CompletedINTERVENTIONAL
Enrollment

117

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

July 31, 2014

Study Completion Date

June 30, 2015

Conditions
Nephrotic Syndrome
Interventions
DRUG

Prednisone

1 mg/kg/day for 4 weeks. Then, the dose will be progressively tapered if the remission will be achieved. For patients who exhibit incomplete remission at this time, high dose steroid will be continued for 4 weeks again before the tapering.

DRUG

acid mycophenolic (Myfortic)

patients will receive prednisone 0.5 mg/kg/day combined with mycophenolic acid (MyforticR) 1440 mg/day. The management of steroid therapy will be identical in both groups, while MyforticR will be continued for six months

Trial Locations (1)

94010

Henri Mondor Hospital, Créteil

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

Assistance Publique - Hôpitaux de Paris

OTHER