Study Evaluating The Safety Of AAB-003 (PF-05236812) In Subjects With Alzheimer's Disease

PHASE1CompletedINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

September 30, 2010

Primary Completion Date

October 31, 2013

Study Completion Date

October 31, 2013

Conditions
Alzheimer's Disease
Interventions
DRUG

AAB-003 (PF-05236812)

0.5 mg/kg AAB-003, IV

DRUG

AAB-003 (PF-05236812)

1 mg/kg AAB-003, IV

DRUG

AAB-003 (PF-05236812)

2 mg/kg AAB-003, IV

DRUG

AAB-003 (PF-05236812)

4 mg/kg AAB-003, IV

DRUG

AAB-003 (PF-05236812)

8 mg/kg AAB-003, IV

OTHER

Placebo

Placebo, IV

Trial Locations (29)

19141

Albert Einstein Medical Center, Philadelphia

20814

Foers Medical Arts Pharmacy, Bethesda

20850

CBH Health, LLC, Rockville

30308

Atlanta Center for Medical Research, Atlanta

33009

MD Clinical, Hallandale

34471

Franck's Pharmacy, Ocala

Munroe Regional Medical Center, Ocala

Renstar Medical Research, Ocala

34481

Advanced Imaging of Ocala, Ocala

39232

Brentwood Behavioral Healthcare, Flowood

Marty's Pharmacy, Flowood

Precise Research Centers, Flowood

49048

Borgess Medical Center, Kalamazoo

Borgess Research Institute, Kalamazoo

KNI/Southwest Michigan Imaging Center, LLC, Kalamazoo

63044

DePaul Health Center, St Louis

63141

Millennium Psychiatric Associates, LLC, Creve Coeur

92025

Early Phase Investigational Center, Escondido

Synergy Clinical Research Center of Escondido, Escondido

07724

Memory Enhancement Center of America, Inc., Eatontown

08837

Pharmacare USA, Edison

07755

Central Jersey Radiology, Oakhurst

19131-1689

Belmont Center for Comprehensive Treatment, Philadelphia

463-707

Seoul National University Bundang Hospital, Department of Neurology, Seongnam-si

Unknown

Inha University Hospital, Department of Neurology, Incheon

135-710

Samsung Medical Center, Department of Neurology, Seoul

136-705

Korea University Anam Hospital, Seoul

138-736

ASAN Medical Center, Seoul

143-914

Konkuk University Medical Center, Department of Neurology, Seoul

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

JANSSEN Alzheimer Immunotherapy Research & Development, LLC

INDUSTRY

lead

Pfizer

INDUSTRY