NCT01193517 - Azacitidine and CAPOX in Metastatic Colorectal Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 31, 2010

Primary Completion Date

November 30, 2016

Study Completion Date

November 30, 2016

Conditions

Colorectal Cancer

Interventions

DRUG

Azacitidine

Starting dose level 75 mg/m2/day subcutaneously on Days 1-5 of a 21 day cycle.

DRUG

Capecitabine

1500 mg/m2/day by mouth twice daily in divided doses on Days 1-14 of a 21 day cycle.

DRUG

Oxaliplatin

Starting dose level 90 mg/m2 by vein on Day 2 of a 21 day cycle.

DRUG

Azacitidine MTD

Highest tolerable dose of combination azacitidine with CAPOX found in Phase I.

Trial Locations (1)

University of Texas MD Anderson Cancer Center, Houston