20
Participants
Start Date
January 31, 2011
Primary Completion Date
December 31, 2016
Study Completion Date
December 31, 2016
IL15-DC Vaccine
Autologous dendritic cells manufactured with GM-CSF, IL15 and loaded with melanoma/HIV peptides and KLH; then activated with LPS and CD40 Ligand. Approximately 9 x 10\^6 DCs will be injected (subcutaneously)total per vaccination visit. Patients will receive four vaccinations at weeks 0, 4, 8 and 12. At each scheduled vaccination the patient will receive a total of 3 injections, i.e., 3 mL injections at each of 3 anatomical locations.Injection sites are in upper and lower extremities. Subsequent DC injections will be rotated to different locations on the upper and lower extremities.
Baylor University Medical Center, Dallas
Lead Sponsor
National Institutes of Health (NIH)
NIH
National Cancer Institute (NCI)
NIH
Baylor Research Institute
OTHER