NCT01179334 - Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters. | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 31, 2010

Primary Completion Date

June 30, 2012

Study Completion Date

May 31, 2013

Conditions

Pulmonary Hypertension

Interventions

DRUG

Riociguat (Adempas, BAY63-2521)

BAY63-2521: 1 mg tid - 2,5 mg tid oral for 12 weeks.

DRUG

Placebo

Placebo for 12 weeks

DRUG

Sildenafil

Participants continued to take daily stable sildenafil background treatment according to their prescriptions.

Trial Locations (25)

1051

Auckland

6020

Innsbruck

8011

Christchurch

9500

Villach

12808

Vseobecna fakultni nemocnice, Prague

13353

Berlin

20246

Hamburg

27100

Pavia

30625

Hanover

35392

Giessen

40138

Bologna

41063

Mönchengladbach

43221

Columbus

50924

Cologne

69126

Heidelberg

80045

Aurora

93042

Regensburg

97074

Würzburg

02903

Providence

01307

Dresden

05-400

Otwock

01-138

Warsaw

08036

Barcelona

CB23 3RE

Papworth Hospital, Cambridge

G81 4DY

Clydebank