Conversion to Embeda With Rescue Trial

PHASE4TerminatedINTERVENTIONAL
Enrollment

684

Participants

Timeline

Start Date

August 31, 2010

Primary Completion Date

April 30, 2011

Study Completion Date

April 30, 2011

Conditions
Chronic DiseasePain
Interventions
DRUG

morphine sulfate and naltrexone hydrochloride (EMBEDA)

Capsules in dose strengths ranging from 20 to 100 mg morphine sulfate with 0.8 to 4 mg of naltrexone hydrochloride taken either once or twice daily with a starting dose calculated using the total daily dose of the current opioid being converted from until a stable dose is achieved or six weeks which ever comes first.

Trial Locations (166)

10530

Drug Trials America, Inc., Hartsdale

11023

Long Island Gastrointestinal Research Group LLP, Great Neck

11561

Office of Roger Kasendorf, DO, Long Beach

11580

North American Partners in Pain Management, LLP, Valley Stream

12801

Adirondack Medical Research Center, Glens Falls

13212

New York Spine & Wellness Center, North Syracuse

14757

Family Health Medical Services PLLC, Mayville

16635

Altoona Center for Clinical Research, PC, Duncansville

17112

Kandra, Fierer, Kuskin Associates, Ltd., Harrisburg

18091

Progressive Pain Solutions, LLC, Wind Gap

18102

Pennsylvania Pain Specialists, PC, Allentown

19014

Ware Medical Associates, PC, Aston Mills

19104

Onuorah Umeh, M.D. P.C, Philadelphia

19152

Founders Research Corporation, Philadelphia

20740

Diseasebusters, LLC, College Park

21208

Office of Steven C. Miller, MD, Pikesville

23502

Sentara Medical Group, NDC Medical Center, Norfolk

25701

Pain Care, PLLC, Huntington

27103

The Center For Clinical Research, LLC, Winston-Salem

27203

Carolina Clinical Research and Consulting, LLC, Asheboro

27205

Carolina Clinical Research and Consulting, LLC, Asheboro

28204

Joint and Muscle Research Institute, Inc., Charlotte

28546

Profen Research Network at ECMA, Jacksonville

28602

Catawba Valley Internal Medicine, Hickory

29118

Low Country Pain Center, LLC, Orangeburg

29406

Low Country Rheumatology, PA, Charleston

Trident Institute of Medical Research, LLC, North Charleston

29412

Pharmacorp Clinical Trials, Inc., Charleston

29576

Clinical Research Authority, LLC, Murrells Inlet

29621

Hartwell Research Group, LLC, Anderson

29650

Internal Medicine of Greer Research LLC, Greer

30024

Herman Clinical Research, LLC, Suwanee

30032

Ialum Clinical Research, LLC, Decatur

30088

Ialum Clinical Research, LLC, Stone Mountain

30338

Perimeter Institute for Clinical Research, Inc., Atlanta

31794

Centers for Pain Management, Tifton

31909

Medical Research and Health Education Foundation, Inc., Columbus

32713

Omega Research Consultants, LLC, DeBary

32746

Omega Research Consultants, LLC, DeBary

33012

International Research Associates, LLC, Hialeah

Palm Springs Research Institute, Inc, Hialeah

33064

Pain Management Strategies, Inc., Pompano Beach

33140

NextPhase Clinical Trials, Inc., Miami Beach

33155

Community Research Foundation, Inc., Miami

33162

Harmony Clinical Research, Inc., North Miami Beach

33175

New Horizon Research Center, Inc., Miami

33408

Office of Laszlo J. Mate, MD, PA, North Palm Beach

33414

Clinical Research Center, LLC, Wellington

33472

Orthopedic Research Institute, LLC, Boynton Beach

33613

Stedman Clinical Trials, LLC, Tampa

33755

Florida Research & Testing, LLC, Clearwater

33781

Advent Clinical Research Centers, Inc., Pinellas Park

33810

Clinical Research of Central Florida, Inc., Lakeland

34238

Sarasota Pain Medicine Research, LLC, Sarasota

34432

West Florida Medical Associate, PA, Dunnellon

34474

Office of Richard E. Promin, MD, PA, Ocala

34741

FPA Clinical Research, LLC, Kissimmee

35005

Adamsville Family Medicine, Adamsville

35209

Office of David McLain, Birmingham

35801

Monte Sano Clinical Research, LLC, Huntsville

Tennessee Valley Pain Consultants Properties, LLC, Huntsville

36117

Office of Vaughn H. Mancha, Jr., PC, Montgomery

36693

Sunbelt Research Group, LLC, Mobile

37075

Comprehensive Pain Specialists, Hendersonville

37404

Chattanooga Medical Research, LLC, Chattanooga

38671

Midsouth Anesthesia Consultants, PLLC, Southhaven

39202

CRC of Jackson, LLC, Jackson

39531

Anesthesia and Pain Control Services, Biloxi

40223

Healing Options, Louisville

40503

The Pain Treatment Center of the Bluegrass, Lexington

42003

Four Rivers Clinical Research, Inc., Paducah

42642

Lakewood Family Practice, Russell Springs

43015

Delaware Smith Clinic Research, Delaware

43551

Whole Family Medical Care LLC, Perrysburg

43764

Jeffrey J. Haggenjos, DO, Inc., New Lexington

44460

Office of Jocelyn F. Shimek, DO, Salem

44883

Office of James Lassiter, Tiffin

45005

Medical Frontiers, LLC, Carlisle

Medical Frontiers, LLC, Franklin

45224

Hightop Medical Research Center, Cincinnati

45236

Sentral Clinical Research Services, Cincinnati

45459

Valley Medical Research, Centerville

46237

Josephson Wallack Munshower Neurology P.C., Indianapolis

46360

Laporte County Institute for Clinical Research Inc., Michigan City

46545

McKinley Research, LLC, Mishawaka

46601

Accelovance, Inc., South Bend

48307

Remedica LLC, Rochester

48314

Michigan Lifestyle Change and Health Center, PC, Sterling

48346

Clarkston Medical Group, PC, Clarkston

48504

Apex Medical Research, AMR, Inc., Flint

48507

East Michigan Medical Associates, Flint

48910

PCM Medical Services, PC, Lansing

50266

Des Moines Orthopaedic Surgeons, PC, West Des Moines

55379

MAPS Applied Research Center, Inc., Shakopee

55435

MAPS Applied Research Center, Inc., Edina

57201

Brown Clinic, PLLP, Watertown

59711

The Reiter Foundation, Inc., Anaconda

60616

Chicago Clinical Research Institute Inc., Chicago

61610

Creve Coeur Family Practice, Creve Coeur

61614

Office of Rebecca Knight, MD, Peoria

63031

Patterson Medical Clinic, Inc., Florissant

63033

Quality Clinical Research Inc., Florissant

65109

Primary Care Medicine, PC, Jefferson City

68114

Medical Pain Relief Clinic, Omaha

68116

Omaha Clinical Research, PC, Omaha

71913

Ouachita Regional Pain Management, Hot Springs

72401

NEA Baptist Clinic, Jonesboro

72450

Hollis Family Medical Clinic, PLC, Paragould

73109

Health Research Institute, LLC, Oklahoma City

Office of Siavash Nael, MD, Inc., Oklahoma City

74074

Associates of Medicine/John D. Williams, MD, PLLC, Stillwater

75110

Corsicana Medical Research, PLLC, Corsicana

75254

DCT - Genesis Neighborhood Research, LLC, Dallas

76710

Hillcrest Family Health Center, Division of Clinical Research, Waco

Hillcrest Family Health Center, Waco

77005

Westbury Medical Clinic, Houston

77034

Accurate Clinical Research, Inc., Houston

77083

Medstar Clinical Research, Houston

78238

Texas Medical Research Associates, LLC, San Antonio

79902

Southwest Urgent Care Center, El Paso

80012

Rocky Mountain Internal Medicine, PC, Aurora

80525

Saint Luke's Medical Clinic, LLC, Fort Collins

80904

Clinicos, LLC, Colorado Springs

84010

Progressive Clinical Research, LLC, Bountiful

85020

Dedicated Clinical Research, Inc, Phoenix

85029

Redpoint Research, Phoenix

85032

Anasazi Internal Medicine, PC, Phoenix

85282

Premiere Phamaceutical Research, LLC, Tempe

85395

Dedicated Clinical Research, Goodyear

85635

Cochise Clinical Research, Sierra Vista

85712

Quality of Life Medical and Research Center, LLC, Tucson

90017

LA Pain & Wellness Institute, Los Angeles

90301

Chrishard Medical Group, Inglewood

90723

Bayview Research Group, LLC, Paramount

90806

Valerius Medical Group and Research Center of Greater Long Beach, Inc., Long Beach

91105

Pasadena Rehabilitation Institute, Pasadena

91607

Bayview Research Group, LLC, Valley Village

91786

Facility Medical Center, Upland

91942

Triwest Research Associates LLC, La Mesa

92078

Rancho Santa Fe Medical Group, Inc., San Marcos

92610

Global Wellness Medical Corporation, Foothill Ranch

92626

CSI Clinical Trials, Costa Mesa

92637

Pacific Coast Pain Management Center, Laguna Hills

92663

Newport Beach Clinical Research Associates, Inc., Newport Beach

92701

Probe Clinical Research Corporation, Santa Ana

Trinity Clinical Trials, Santa Ana

95032

Samaritan Center for Medical Research, Los Gatos

95661

Quality Control Research, Inc., Roseville

95821

Northern California Research, Sacramento

95842

Quality Control Research, Inc., Sacramento

97035

Portland Rheumatology Clinic, LLC, Lake Oswego

97222

Office of Joseph E. Yankee, DO, PC, Milwaukie

98026

Washington Center for Pain Management PLLC, Edmonds

06040

ProHealth Physicians PC, Manchester

06460

Milford Physician Services, PC, Milford

02301

Beacon Clinical Research, LLC, Brockton

02720

Ronald J. Rapoport, MD, PC, Fall River

02154

Boston Paincare Center, Inc., Waltham

08004

Atco Medical Associates, PC, Atco

07823

Office of John V. Bernard, MD, Belvidere

07202

Central Jersey Medical Research Center, Inc., Elizabeth

07601

Center for Pain Management, Hackensack

08035

Advocare Heights Primary Care, Haddon Heights

07036

NJ Heart, LLC, Linden

07702

Spine and Pain Centers, PA, Shrewsbury

08611

Premier Research, Inc., Trenton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY