NCT01179009 - Treatment Resistant Depression (Pilot) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

June 6, 2014

Study Completion Date

June 5, 2015

Conditions

Depressive Disorder, Treatment-Resistant

Interventions

DRUG

Ketamine

Controlled IV ketamine infusion (0.00225mg/kg-min. \[18% (0.0125 mg/kg-min.).

DRUG

Clonidine

Participants will receive an approximately 5-day pretreatment of clonidine (max. dose 1mg/day divided doses) prior to and throughout the ketamine infusion.

DRUG

placebo

IV saline (i.e. placebo ketamine)

Trial Locations (1)

63110

Washington University School of Medicine, St Louis

All Listed Sponsors

collaborator

Florida Atlantic University

OTHER

lead

Washington University School of Medicine

OTHER