Role of Hypersensitivity to Female Sex Hormones in Women With Unexplained Recurrent Pregnancy Loss

PHASE2UnknownINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 30, 2010

Primary Completion Date

June 30, 2011

Study Completion Date

December 31, 2011

Conditions
Abortion, Recurrent
Interventions
DRUG

Skin test panel

"Skin testing 4 sex hormones will be performed during the luteal phase of the subject's menstrual cycle by study investigators.~Hormones:~1. Progesterone 1mmol/L~2. Estradiol 1mmol/L~3. Estrone 3mmol/L~4. Estriol 3mmol/l~ Controls:~5. Saline (NaCl) 0.9%~6. Ethyl Oleate with 10% Benzyl Alcohol~7. Histamine phosphate 1mg/ml (epicutaneous- prick test)"

DRUG

Skin test panel

"Skin testing 4 sex hormones will be performed during the luteal phase of the subject's menstrual cycle by study investigators.~Hormones:~1. Progesterone 1mmol/L~2. Estradiol 1mmol/L~3. Estrone 3mmol/L~4. Estriol 3mmol/l~ Controls:~5. Saline (NaCl) 0.9%~6. Ethyl Oleate with 10% Benzyl Alcohol~7. Histamine phosphate 1mg/ml (epicutaneous- prick test)"

Trial Locations (1)

H1125

RECRUITING

Depts. Gynecology and Obstetrics and 3rd Dept of Internal Medicine, Budapest

Sponsors
All Listed Sponsors
collaborator

Semmelweis University

OTHER

lead

EVE Medical Systems Ltd.

INDUSTRY