Study for Women With Platinum Resistant Ovarian Cancer Evaluating EC145 in Combination With Doxil® (PROCEED)

PHASE3TerminatedINTERVENTIONAL
Enrollment

441

Participants

Timeline

Start Date

April 22, 2011

Primary Completion Date

May 31, 2015

Study Completion Date

September 8, 2015

Conditions
Ovarian Cancer
Interventions
DRUG

EC145

IV bolus on days 1,3,5 and 15,17,19 of a 4-week cycle

DRUG

Pegylated Liposomal Doxorubicin (PLD/Doxil®/Caelyx®)

50 mg/m2 (calculated on the basis of ideal body weight) every 4 weeks. Dose reductions permitted for toxicity.

DRUG

placebo

IV bolus on days 1,3,5 and 15,17,19 of a 4-week cycle

DRUG

EC20

During the screening period participants will receive a single intravenous administration of EC20 prior to SPECT imaging

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Endocyte

INDUSTRY