36
Participants
Start Date
March 31, 2008
Primary Completion Date
July 31, 2014
Study Completion Date
July 31, 2014
Everolimus
First phase of the study:RAD001 (everolimus) will be administered per os every Monday, one week before then during the radiotherapy and will be continued for 3.5 weeks after the end of the radiotherapy. Chemotherapy is given 4.5 weeks after the end of radiotherapy. Three patient cohorts are planned, receiving 10, 20 and 50 mg of RAD001 per week.Second phase of the study:RAD001 (everolimus) will be administered per os every day one week before then during the radiotherapy and will be continued for 3.5 weeks after the end of radiotherapy. Chemotherapy is given 4.5 weeks after the end of radiotherapy. Three patient cohorts are planned, receiving 2.5, 5 and 10 mg of RAD001 per day.The two phases of the study may be conducted independently and in parallel.
RECRUITING
Institut Gustave Roussy, Villejuif
Collaborators (1)
Novartis
INDUSTRY
Gustave Roussy, Cancer Campus, Grand Paris
OTHER