Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer

PHASE3TerminatedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

February 28, 2011

Primary Completion Date

October 31, 2011

Study Completion Date

October 31, 2011

Conditions
Squamous Cell CarcinomaHead and Neck Cancer
Interventions
BIOLOGICAL

Talimogene Laherparepvec

Administered by intratumoral injection

RADIATION

Radiation

70 grays of radiation administered in 35 fractions over 7 weeks

DRUG

Cisplatin

Administered by intravenous infusion

Trial Locations (6)

23298

VCU Massey Cancer Center, Richmond

29425

Medical Univesity of South Carolina, Charleston

40202

James Graham Brown Cancer Center, University of Louisville, Louisville

44718

Gabrail Cancer Center, Canton

46260

Investigative Clinical Research of Indiana, Indianapolis

SE1 7EH

The Royal Marsden Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

lead

BioVex Limited

INDUSTRY