NCT01160822 - To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee | Biotech Hunter

Enrollment

169

Participants

Timeline

Start Date

April 30, 2010

Primary Completion Date

July 31, 2011

Study Completion Date

July 31, 2011

Conditions

Osteoarthritis

Interventions

BIOLOGICAL

Canakinumab

Intra-articular injection

DRUG

Placebo to canakinumab

Intra-articular injection

DRUG

Naproxen

Tablets for oral administration

DRUG

Placebo to Naproxen

Tablets for oral administration

Trial Locations (13)

Altoona Center for Clinical Research, Duncansville

Pinnacle Research Group, LLC, Anniston

Volunteer Research Group, Knoxville

Rush-Presbyterian St. Lukes Medical Center, Chicago

Cotton O'Neil Clinical Research Institute, Topeka

Arizona Arthritis & Rheumatology Research, PLLC, Mesa

Westlake Medical Research, Westlake Village

San Diego Arthritis & Osteoporosis Medical Clinic, San Diego

Novartis Investigative site, Helsinki

Novartis Investigative site, Kuopio

Novartis Investigative site, Créteil

Novartis Investigative site, Berlin

Novartis Investigative site, Erlangen