Treatment of the optImuM Dose of calcineUrin Inhibitor and Mycophenolate Sodium in Kidney Recipients

PHASE4CompletedINTERVENTIONAL
Enrollment

350

Participants

Timeline

Start Date

April 1, 2010

Primary Completion Date

October 30, 2016

Study Completion Date

November 30, 2016

Conditions
Kidney Transplantation
Interventions
DRUG

routine dose tacrolimus and less myfortic

oral regular dose of tacrolimus + less dose of myfortic trough level of tacrolimus will be 5-10 ng/mL and oral myfortic dose will be 180-360 mg twice a day

DRUG

reduced dose tacrolimus and conventional myfortic

low dose of tacrolimus + maximum dose of myfortic target trough level of tacrolimus should be reduced to 2-5 ng/mL for 3 months after randomization and oral MPS dose increased to 540-720mg twice a day

Trial Locations (1)

138-736

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
collaborator

Seoul National University Hospital

OTHER

collaborator

Samsung Medical Center

OTHER

lead

Asan Medical Center

OTHER