Study to Assess Brincidofovir Treatment of Serious Diseases or Conditions Caused by Double-stranded DNA Viruses

PHASE3CompletedINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

December 31, 2010

Primary Completion Date

December 31, 2012

Study Completion Date

December 31, 2012

Conditions
Double-stranded DNA Virus
Interventions
DRUG

Brincidofovir

Brincidofovir (BCV) was administered orally either once or twice weekly for up to 3 months. Treatment may have been extended for an additional 3 months depending a satisfactory review of safety parameters. Subjects could not receive more than a total of 6 months of treatment with BCV without prior approval.

Trial Locations (37)

10029

Mt. Sinai, New York

10032

Columbia University, New York

10065

Memorial Sloan Kettering Cancer Institute, New York

15213

UPMC, Pittsburgh

15224

Childrens Hospital of Pittsburgh, Pittsburgh

19104

Children's Hospital of Philadelphia, Philadelphia

20010

Children's National Medical Center, Washington D.C.

20892

NIH, Bethesda

27599

University of North Carolina at Chapel Hill, Chapel Hill

27710

Duke University Medical Center, Durham

28203

Levine Children's Hospital Carolina Medical Center, Charlotte

43205

Nationwide Children's Hospital, Columbus

44195

Cleveland Clinic, Cleveland

45229

Cincinnati Childrens Hospital, Cincinnati

48109

University of Michigan, Ann Arbor

52242

University of Iowa, Iowa City

53226

Medical College of Wisconsin, Milwaukee

55455

University of Minnesota, Minneapolis

60637

University of Chicago, Chicago

63110

St. Louis Children's Hospital, St Louis

70118

Childrens Hospital LSU, New Orleans

77030

UT MD Anderson Cancer Center, Houston

80045

Children's Hospital of Colorado, Aurora

84143

Intermountain BMT program LDS Hospital, Salt Lake City

90027

Children's Hospital of LA, Los Angeles

90095

UCLA Department of Medicine, Los Angeles

92354

Loma Linda University Hospital, Loma Linda

92868

CHOC Children's, Orange

94143

Univeristy of San Francisco, San Francisco

94304

Lucile Packard Children's Hospital, Stanford

97239

Oregon Health and Science University, Portland

98109

University of Washington-Fred Hutchinson Cancer Center, Seattle

02111

Tufts Medical Center, Boston

02115

Brigham and Womens Hospital, Boston

68198-5130

University of Nebraska Medical Center, Omaha

07601

Hackensack University Medical Center, Hackensack

76104-2796

Cook Children's Medical Center, Fort Worth

Sponsors
All Listed Sponsors
lead

Jazz Pharmaceuticals

INDUSTRY