A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

PHASE1CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

November 1, 2024

Study Completion Date

November 1, 2024

Conditions
Newly Diagnosed Pediatric Pontine GliomaNewly Diagnosed Pediatric High Grade GliomaRecurrent Pediatric High Grade GliomaRecurrent Pediatric Low Grade Glioma
Interventions
BIOLOGICAL

HLA-A2 restricted glioma antigen peptides vaccine

Vaccine given every 3 weeks

BIOLOGICAL

Poly-ICLC

Vaccine given every 3 weeks

Trial Locations (1)

15224

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Ellie Kavalieros Fund

UNKNOWN

collaborator

Translational Brain Tumor Research Fund

UNKNOWN

collaborator

Connor's Cure

OTHER

lead

James Felker

OTHER