A Safety and Tolerability Study of MEDI-570 in Systemic Lupus Erythematosus

PHASE1TerminatedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

May 31, 2010

Primary Completion Date

July 31, 2012

Study Completion Date

July 31, 2012

Conditions
Lupus Erythematosus, Systemic
Interventions
OTHER

Placebo

A single double-blind dose of placebo matched to MEDI-570 subcutaneous injection on Day 1.

BIOLOGICAL

MEDI-570 0.03 MG

A single open-label dose of MEDI-570, 0.03 milligram (mg) subcutaneous injection on Day 1.

BIOLOGICAL

MEDI-570 0.1 MG

A single open-label dose of MEDI-570, 0.1 mg subcutaneous injection on Day 1.

BIOLOGICAL

MEDI-570 0.3 MG

A single double-blind dose of MEDI-570, 0.3 mg subcutaneous injection on Day 1.

BIOLOGICAL

MEDI-570 1 MG

A single double-blind dose of MEDI-570, 1 mg subcutaneous injection on Day 1.

Trial Locations (17)

Unknown

Research Site, Winston-Salem

Research Site, Columbus

Research Site, London

Research Site, Chihuahua City

Research Site, Guadalajara

Research Site, México

Research Site, Lima

Research Site, Trujillo

Research Site, Cape Town

Research Site, Johannesburg

Research Site, Long Beach

Research Site, San Leandro

Research Site, Fort Lauderdale

Research Site, Ocala

Research Site, Atlanta

Research Site, Lansing

Research Site, New York

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

MedImmune LLC

INDUSTRY