Evaluation of Simplified Antiretroviral Treatment Strategies in HIV Infected Children Treated by Antiretroviral (ARV) Before One Year of Age

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

161

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

April 30, 2015

Study Completion Date

April 30, 2015

Conditions
HIV Infections
Interventions
DRUG

AZT-3TC-LPV/r twice a day

AZT sirup (10mg/ml): 4 mg/kg or 180 mg/m2 twice daily 3TC sirup (10mg/ml): 4 mg/kg twice daily LPV/r sirup (80/20 mg/ml): 12 mg/kg twice daily

DRUG

ABC-3TC-EFV once a day

ABC sirup (20mg/ml): 16 mg/kg once daily in the morning 3TC sirup (10mg/ml): 8 mg/kg once daily in the morning EFV sirup (30mg/ml): 25 mg/kg once daily in the morning before food intake

Trial Locations (4)

Unknown

Service de maladies infectieuses - CHU Charles de Gaulle, Ouagadougou

Service de pédiatrie - CHU Yalgado Ouedraogo, Ouagadougou

CEPREF, Abidjan

FSU abobo-Avocatier, Abidjan

All Listed Sponsors
collaborator

European and Developing Countries Clinical Trials Partnership (EDCTP)

OTHER_GOV

collaborator

Public Research Centre Health, Luxembourg

OTHER

collaborator

Ministry of Foreign Affairs, Luxembourg

UNKNOWN

collaborator

University of Ouagadougou, Burkina Faso

OTHER

collaborator

Programme PAC-CI, Site ANRS-MIE de Côte d'Ivoire

OTHER

collaborator

Ministry of Health, Rwanda

OTHER_GOV

collaborator

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

collaborator

University of Bordeaux

OTHER

collaborator

Institut de Sante Publique, d'Epidémiologie et de Développement

UNKNOWN

collaborator

Université Montpellier

OTHER

collaborator

University of Paris 5 - Rene Descartes

OTHER

collaborator

Queen Fabiola Children's University Hospital

OTHER

lead

ANRS, Emerging Infectious Diseases

OTHER_GOV

NCT01127204 - Evaluation of Simplified Antiretroviral Treatment Strategies in HIV Infected Children Treated by Antiretroviral (ARV) Before One Year of Age | Biotech Hunter | Biotech Hunter