A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

176

Participants

Timeline

Start Date

May 31, 2010

Primary Completion Date

August 31, 2013

Study Completion Date

August 31, 2013

Conditions
Allergic Asthma
Interventions
DRUG

Omalizumab

Omalizumab was supplied as a sterile, white, preservative-free, lyophilized powder in single-use vials that was reconstituted with sterile water for injection.

DRUG

Placebo

Placebo contained the same ingredients as the omalizumab formulation, excluding omalizumab.

DRUG

Asthma therapies

Participants could receive 1 or more of the following medications as concomitant asthma therapy: Inhaled corticosteroids; long acting beta-agonists; zafirlukast or other leukotriene receptor antagonist; zileuton or other 5-lipoxygenase enzyme inhibitors; oral, inhaled, and/or nasal anticholinergic therapy; mast-cell stabilizers; theophyllines; chronic oral corticosteroids, defined as a minimum dose of oral prednisone of 2 to 40 mg/day or 5 to 80 mg every other day.

Trial Locations (100)

10022

New York

10304

Staten Island

10423

The Bronx

10461

The Bronx

10465

The Bronx

10552

Mount Vernon

10940

Middletown

11501

Mineola

11570

Rockville Centre

12205

Albany

12550

Newburgh

12561

New Paltz

14760

Olean

15009

Beaver

15213

Pittsburgh

15221

Pittsburgh

16601

Altoona

17013

Carlisle

17110

Harrisburg

19013

Upland

20878

Gaithersburg

21042

Ellicott City

21236

Baltimore

23298

Richmond

26003

Wheeling

27262

High Point

28801

Asheville

29607

Greenville

30501

Gainesville

31707

Albany

31904

Columbus

32503

Pensacola

33401

West Palm Beach

33470

Loxahatchee Groves

33613

Tampa

33744

Bay Pines

33765

Clearwater

34471

Ocala

35801

Huntsville

37909

Knoxville

40513

Lexington

45434

Beavercreek

45458

Centerville

46804

Fort Wayne

46815

Fort Wayne

53715

Madison

58103

Fargo

58104

Fargo

60068

Park Ridge

60612

Chicago

62034

Glen Carbon

63104

Sasint Louis

63110

St Louis

63141

St Louis

64068

Liberty

65807

Springfield

66210

Overland Park

66606

Topeka

68123

Bellevue

68130

Omaha

70002

Metairie

70471

Mandeville

72205

Little Rock

73112

Oklahoma City

74133

Tulsa

75032

Heath

75044

Garland

75230

Dallas

75231

Dallas

78233

San Antonio

78251

San Antonio

78681

Round Rock

79925

El Paso

80112

Centennial

80233

Thornton

90025

Los Angeles

90064

Los Angeles

91344

Granada Hills

91607

Studio City

93301

Bakersfield

93720

Fresno

93726

Fresno

94063

Redwood City

94104

San Francisco

94401

San Mateo

94558

Napa

94598

Walnut Creek

95819

Sacramento

98405

Tacoma

99204

Spokane

06708

Waterbury

02114

Boston

01440

Gardner

02747

North Dartmouth

02780

Taunton

07016

Cranford

08820

Edison

08844

Hillsborough

07044

Verona

02865

Lincoln

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY