A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma

PHASE1/PHASE2CompletedINTERVENTIONAL

Enrollment

144

Participants

Timeline

Start Date

May 31, 2010

Primary Completion Date

December 31, 2011

Study Completion Date

January 31, 2012

Conditions

GlaucomaOcular Hypertension

Interventions

DRUG

INO-8875

eye drops for 14 days in one eye

DRUG

Placebo

Matched vehicle-control

Trial Locations (1)

Lugene Eye Institute, Glendale