OGX-427 in Castration Resistant Prostate Cancer Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

September 30, 2010

Primary Completion Date

October 31, 2012

Study Completion Date

June 30, 2014

Conditions
Castration Resistant Prostate Cancer
Interventions
DRUG

OGX-427

OGX-427: Starting within 5 days of randomization, three loading doses at 600 mg IV within the first 10 days of initiating treatment, followed by weekly doses of 1000 mg IV

DRUG

Prednisone

"Control Arm:~Prednisone: 5 mg BID orally starting within 4 days following randomization~Experimental Arm:~Prednisone: 5 mg BID orally starting within 4 days following randomization and at least 24 hours prior to first loading dose of OGX-427"

Trial Locations (6)

98109

University of Washington/Seattle Cancer Care Alliance, Seattle

V1Y 5L3

BC Cancer Agency - Centre for the Southern Interior, Kelowna

V5Z 4E6

BC Cancer Agency - Vancouver Centre, Vancouver

R3E 0V9

CancerCare Manitoba, Winnipeg

L8V 5C2

Juravinski Cancer Centre, Hamilton

M5G 2M9

Princess Margaret Hospital, Toronto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Achieve Life Sciences

INDUSTRY

lead

British Columbia Cancer Agency

OTHER