Study of SyB L-0501 in Combination With Rituximab to Treat Relapsed/Refractory Diffuse Large B-Cell Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

April 30, 2010

Primary Completion Date

October 31, 2011

Study Completion Date

October 31, 2011

Conditions
Non-Hodgkin's LymphomaLymphoma, Large CellDiffuse, Mantle Cell Lymphoma, LymphomaFollicular LymphomaLarge B-Cell, Diffuse
Interventions
DRUG

SyB L-0501

"The administration of SyB L-0501 at 120 mg/m\^2/day by intravenous infusion on day 2 and 3 of each 21-day cycle with up to 6 cycles. Dose modifications are permitted from 2nd cycle according to dose reduction schedule.~SyB L-0501 60 mg/m\^2, 90 mg/m\^2 or 120 mg/m\^2/day on Day 2 and Day 3 will be followed by 18 days of observation."

DRUG

Rituximab

The administration of rituximab at 375 mg/m\^2/day by intravenous infusion on day 1 of each 21-day cycle with up to 6 cycles. Dose modifications are not permitted.

Trial Locations (25)

Unknown

Nagoya

Akita

Matsuyama

Fukuoka

Kurume

Maebashi

Sapporo

Kanazawa

Kagoshima

Isehara

Ninomaru

Kyoto

Sendai

Kita-ku

Kurashiki

Hidaka

Izumo

Chuo-ku

Seo-gu

Jung-gu

Goyang-si

Hwasun-gun

Gangnam-gu

Seodaemun-gu

Songpa-gu

Sponsors
All Listed Sponsors
lead

SymBio Pharmaceuticals

INDUSTRY