Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down Syndrome

PHASE4CompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

July 31, 2008

Primary Completion Date

July 31, 2011

Study Completion Date

August 31, 2011

Conditions
Down Syndrome
Interventions
DRUG

Memantine

The drug dosage will follow memantine's standard titration schedule (i.e., 5 mg/d week one, 5 mg/BID week two, 5 \& 10 mg/d divided dose week three, 10mg/BID week four).

DRUG

Placebo

These are identically-looking pills to those in the Memantine Arm.

Trial Locations (1)

80045

The Children's Hospital, Aurora

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Forest Laboratories

INDUSTRY

lead

University of Colorado, Denver

OTHER