Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

July 31, 2012

Study Completion Date

July 31, 2012

Conditions
Aplastic Anemia
Interventions
BIOLOGICAL

anti-thymocyte globulin

On days -3 to -1

BIOLOGICAL

filgrastim

Beginning on day 4 and continuing until blood counts recover

DRUG

Fludarabine

30mg/M2 once daily IV on days -6 to -2

DRUG

Cyclophosphamide

60 mg/kg IV on day-3 and -2

PROCEDURE

CD3±CD19 depleted hematopoietic stem cell transplantation

Immunogenetic depletion on CliniMACS

Trial Locations (1)

138-736

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
lead

Asan Medical Center

OTHER

NCT01105273 - Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia | Biotech Hunter | Biotech Hunter