To Explore The Potential For PF-04531083 To Effect The Blood Concentrations Of Simvastatin And Its Main Acid Metabolite Following Co-Administration Of Both Medications

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

March 31, 2010

Primary Completion Date

May 31, 2010

Study Completion Date

May 31, 2010

Conditions
Chronic Pain
Interventions
DRUG

PF-04531083

PF-04531083: 100mg to be dosed twice daily as a suspension from Day 2 through Day 14 of the study.

DRUG

simvastatin

Simvastatin: a single 20mg tablet to be given on Days 1 and 14 of the study.

DRUG

PF-04531083

PF-04531083: a dose to be selected depending on results from Cohort 1 to be dosed twice daily as a suspension from Day 2 through Day 14 of the study.

DRUG

simvastatin

Simvastatin: a single 20mg tablet to be given on Days 1 and 14 of the study.

Trial Locations (1)

1070

Pfizer Investigational Site, Brussels

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY